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Controlled trials that show benefit usually use specific forms and doses. If CardioGenix provides ingredients below the efficacious range, expect little effect. If it uses proprietary blends without disclosing amounts, efficacy is harder to judge.
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Meaningful outcomes vs. surrogate markers:
Many supplement studies measure surrogate endpoints (blood pressure, blood lipids, inflammatory markers). While those are useful, the gold standard is reduction in clinical events (heart attack, stroke, death). Few supplements have compelling evidence for event reduction in general populations.
Official website
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